The ASE database can be connected using the ODBC driver only for the PowerBuilder installable cloud app.
To configure ODBC for Adaptive Server Enterprise (using ASE 16 as an example):
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Install the ODBC driver for ASE 16.
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Open the ODBC Data Source Administrator (64-bit) tool (in the Windows search bar (or press Win + Q), type "ODBC" and then select ODBC Data Source (64-bit)).
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On the System DSN tab, click Add. In the Create New Data Source dialog, select Adaptive Server Enterprise driver which was just installed, and then click Finish.
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Create an ODBC data source by following the numerical order in the figure below. Remember to replace the database information with your own ones.