PowerBuilder 2021 MR 1506 has the following known issues:
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PowerClient/PowerServer applications crash when multiple instances are run, and the event viewer indicates an error with PBSHR.dll.
Please refer to the following page for solutions: https://www.appeon.com/developers/get-help/knowledgebase/powerclientpowerserver-applications-crash-when-multiple-instances-are-run-powerbuilder-2021-build-1506.html.
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When the PowerClient/PowerServer application is started with the background service, in Chrome/Edge version 98, the application will be started twice.
Please refer to the following page for solutions: https://www.appeon.com/developers/get-help/knowledgebase/powerclientpowerserver-application-started-twice-chromeedge-version-98.html.